REJURAN® polynucleotides (PN) are slow-degrading DNA fragments derived from wild salmon.

REJURAN® PN is a more concentrated form of PDRN (Polydeoxyribonucleotide) or salmon sperm-derived DNA.

REJURAN® is a colourless and transparent gel form that maintains a specific viscosity which functions as a scaffold. This specific viscosity addresses wrinkles, fine lines and scars
in a natural way.

DOT™ PN is a highly bio-compatible DNA fragment that has been purified and extracted from Korean Chum Salmon O.Keta, which has the closest DNA base composition to the human body.

• Repairs Skin Damage – Rejuran helps restore damaged skin cells and stimulates the growth of new, healthy ones, making it beneficial for individuals with sensitive or irritated skin.

• Enhances Hydration – It improves the skin’s ability to retain moisture, resulting in a plumper and more refreshed appearance.

• Boosts Elasticity – By encouraging collagen production, Rejuran helps maintain firm and supple skin.

• Calms Irritated Skin – Its anti-inflammatory properties reduce redness and irritation, making it a suitable option for those with sensitive or acne-prone skin.

• Uses Natural Ingredients – The polynucleotides used are biocompatible and support the skin’s natural healing process.

• Minimal Downtime – Most patients experience mild redness and swelling, which typically resolves within a few days.

• Long-Term Benefits – With multiple sessions, Rejuran gradually improves skin quality, and the effects can last for several months.

• Suitable for Most Skin Types – Generally well-tolerated, even by individuals with sensitive skin.

• Multiple Sessions Needed – For the best results, 3–4 treatments are usually required, spaced about four weeks apart, adding to the time and cost involved.

• Can Be Expensive – Treatment costs vary depending on the clinic and location.

• Temporary Side Effects – Some individuals may experience mild swelling, bruising, or redness at the injection sites, but these effects are usually short-lived.

• Mild Discomfort – While numbing cream is applied, some patients may still feel discomfort during the procedure.

• Gradual Results – Unlike some treatments that offer instant results, Rejuran requires time as the skin gradually regenerates.

• Not Ideal for Severe Aging Concerns – It may not provide significant improvement for deep wrinkles or severe sagging compared to other options like dermal fillers, biostimulators, or surgical treatments.

• Potential Risks – Although rare, complications such as infections or adverse reactions can occur if the treatment is not performed under proper conditions. Blindness or stroke may be an extremely rare side effect of Rejuran, as is the case with all Dermal Fillers.

• Focuses on long-term skin regeneration and overall health improvement.

• Does not add volume or alter facial contours.

• Does not affect muscle movement.

• Is considered safer than Dermal Fillers as it is an intra-dermal treatment.

Yes, Rejuran is considered a low-risk treatment, as polynucleotides are derived from purified salmon DNA, which is biocompatible and well-tolerated by most individuals. However, as with any medical procedure, risks exist, so it should only be performed by a qualified practitioner.

Common side effects are typically mild and temporary, including:

• Redness

• Swelling

• Bruising at injection sites

These usually resolve within a few days, depending on the individual.

Common areas that can benefit from Rejuran include:

• Face

• Neck

• Hands

• Under-eye area

Rejuran may not be suitable for individuals who:

• Are pregnant or breastfeeding

• Have active skin infections or severe acne

• Have known allergies to any ingredients in the treatment.